An expressed sequence tag or EST is a short sub-sequence of a cDNA sequence. They may be used to identify gene transcripts, and are instrumental in gene discovery and gene sequence determination. The identification of ESTs has proceeded rapidly, with approximately 74.2 million ESTs now available in public databases (e.g. GenBank 1 January 2013, al...
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<molecular biology> Expressed sequence tags are sequence tagged sites derived from cDNAs. ... See: sequence tagged site. ... Acronym: EST ... (06 Aug 1998) ...
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DNA sequence derived by sequencing an end of a random cDNA clone from a library of interest. Usually, tens of thousands of such ESTs are generated as part of genome projects. These ESTs provide a rapid way of identifying cDNAs of interest, based on their sequence ‘tag`; they can then be purchased cheaply, obviating the need to screen a library.
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